Recent Publications

Low-Cost, High-Pressure-Synthesized Oxygen-Entrapping Materials to Improve Treatment of Solid Tumors.

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  • Bi, J., Witt, E., Voltarelli, V. A., Feig, V. R., Venkatachalam, V., Boyce, H., McGovern, M., Gutierrez, W. R., Rytlewski, J. D., Bowman, K. R., Rhodes, A. C., Cook, A. N., Muller, B. N., Smith, M. G., Ramos, A. R., Panchal, H., Dodd, R. D., Henry, M. D., Mailloux, A., Traverso, G., Otterbein, L. E., Byrne, J. D., Low-Cost, High-Pressure-Synthesized Oxygen-Entrapping Materials to Improve Treatment of Solid Tumors. Adv. Sci. 2023, 2205995. 

Delivery of therapeutic carbon monoxide by gas-entrapping materials.

  • Byrne, J. D., Gallo, D., Boyce, H., Becker, S. L., Kezar, K. M., Cotoia, A. T., Feig, V. R., Lopes, A., Csizmadia, E., Longhi, M. S., Lee, J. S., Kim, H., Wentworth, A. J., Shankar, S., Lee, G. R., Bi, J., Witt, E., Ishida, K., Hayward, A., Kuosmanen, J. L. P., Jenkins, J., Wainer, J., Aragon, A., Wong, K., Steiger, C., Jeck, W. R., Bosch, D. E., Coleman, M. C., Spitz, D. R., Tift, M., Langer, R., Otterbein, L. E., & Traverso, G. (2022). Delivery of therapeutic carbon monoxide by gas-entrapping materials. Science Translational Medicine, 14(651), eabl4135. 
Please review our lab member's previous publications below!
  • Sadeghi I, Byrne JD, Shakur R, Langer R. Engineered drug delivery devices to address global health challenges. Journal of Controlled Release. 2021, 331: 503-514. PMID: 33516755 
  • Byrne JD, Young CC, Chen MX, Wentworth AJ, Pursley J, Kirtane AR, Remillard KA, Hancox CI, Hua T, Tamang SM, Collins JE, Ishida K, Hayward A, Edgington SK, Schoenfeld JD, Jeck WR, Traverso G. Personalized radiation attenuating materials for gastrointestinal mucosal protection. Advanced Science. 2021, 8: 2100510.  
  • Chu JN, Ghenand O, Collins J, Byrne JD, Wentworth A, Chai PR, Dadabhoy F, Hur C, Traverso G. Thinking green: mask strategies to reduce cost and waste. BMJ Open. 2021, 11: e048687.
  • Byrne JD, Huang HW, McRae JC, Babaee S, Soltani A, Becker SL, Traverso G. Devices for drug delivery in the gastrointestinal tract: a review of systems physically interacting with the mucosa for enhanced delivery. Advanced Drug Delivery Reviews. 2021, 177:  113926.
  • Dee EC, Byrne JD, Wo JY. Evolution of the role of radiotherapy for anal cancer. Cancers. 2021, 13(6), 1208.
  • Sadtler K, Collins J, Byrne JD, Langer R. Parallel evolution of materials chemistry and immunology: integrating mechanistic biology with materials design. Advanced Drug Delivery Reviews.  2020, S0169-409X: 30067-3. PMID: 32589903
  • Byrne JD, Wentworth AJ, Chai PR, Huang HW, Babaee S, Li C, Becker SL, Tov C, Min S, Traverso G. Injection Molded Autoclavable, Scalable, Conformable (iMASC) system for aerosol-based protection. BMJ Open. 2020, 10: e039120. PMID: 32641368 
  • Byrne JD, Botticello T, Shih HA, Loeffler JS, Oh KS. Post-Operative Radiation Therapy to the Surgical Cavity with Standard Fractionation in Patients with Brain Metastases. Scientific Reports. 2020, 10: 6331. PMID: 32286375
  • Wentworth AJ, Byrne JD, Orguc S, Sands J, Maji S, Tov C, Babaee S, Huang HW, Boyce H, Chai PR, Min S, Li C, Chu JN, Som A, Becker SL, Gala M, Chandrakasan A, Traverso G. Multi-Institutional Prospective Evaluation of the Transparent, Elastomeric, Adaptable, Long-lasting (TEAL) Respirator. ACS Pharmacology & Translational Science. 2020, 3 (6): 1076-1082. 
  • Byrne JD, Yeh JJ, DeSimone JM. Use of Iontophoresis for the Treatment of Cancer. Journal of Controlled Release. 2018, 284: 144-151. PMID: 29908892
  • Byrne JD, Jajja MRN, O’Neill AT, Schorzman A, Keeler AW, Luft JC, Zamboni WC, DeSimone JM, Yeh JJ. Impact of Formulation on the Iontophoretic Delivery of the FOLFIRINOX Regimen for the Treatment of Pancreatic Cancer. Cancer Chemotherapy and Pharmacology. 2018, 81(6): 991-998. PMID: 29603014
  • Byrne JD, Royce TJ, Loeffler JS. Stereotactic Conformal Radiation Therapy in the Treatment of Benign and Low-grade Brain Tumors. Translational Cancer Research. 2017, 6 (7): S200-S204.
  • Bowerman CJ, Byrne JD, Chu KS, Schorzman AN, Keeler AW, Sherwood CA, Perry JL, Luft JC, Darr DB, Deal AM, Napier ME, Zamboni WC, Sharpless NE, Perou CM, DeSimone JM. PLGA Nanorod Improves Docetaxel Efficacy in Taxane-Resistant Triple-Negative Breast Cancer. Nano Letters. 2017, 17 (1): 242-248. PMID: 27966988 
  • Byrne JD, Stephens R, Isaacson A, Yu H, Burke C. Image-Guided Percutaneous Drainage for Treatment of Post-Surgical Anastomotic Leak in Patients with Crohn’s Disease. Journal of Crohn’s and Colitis. 2016, 10 (1): 38-42. PMID: 26417048
  • Byrne JD, Jajja MRN, Schorzman A, Keeler AW, Luft JC, Zamboni WC, DeSimone JM, Yeh JJ. Iontophoretic Device Delivery for the Localized Treatment of Pancreatic Ductal Adenocarcinoma. Proceedings of the National Academy of Sciences. 2016, 113 (8): 2200-5. PMID: 26858448 
  • Byrne JD, Jajja MRN, O’Neill AT, Bickford LR, Keeler AW, Little RE, Moffitt R, Stack C, Nelson M, Brooks CR, Lee W, Luft JC, Napier ME, Darr D, Anders CK, Stack R, Tepper JE, Wang AZ, Zamboni WC, Yeh JJ, DeSimone JM. Local Iontophoretic Administration of Cytotoxic Therapies to Solid Tumors. Science Translational Medicine. 2015, 7 (273) ra14. PMID: 25653220 
  • Roberts R, Eitas T, Byrne JD, Short P, McKinnon K, Reisdoff S, Luft JC, DeSimone JM, Ting J. Towards Programming Immune Tolerance through Geometric Manipulation of Phosphatidylserine. Biomaterials. 2015, 72: 1-10. PMID: 26325217 
  • Xu J, Wong D, Byrne JD, Chen K, Bowerman C, DeSimone JM. Future of the Particle Replication in Nonwetting Templates (PRINT) Technology. Angewandte Chemie. 2013, 52 (26): 6580-6589. PMID: 23670869
  • Dunn S, Byrne JD, Chen K, Perry J, DeSimone JM. Fabricating Better Medicine for Cancer. ACS Macro Letters. 2013, 2: 393-397. PMID: 23772351   
  • Wang Y, Byrne JD, Napier ME, DeSimone JM. Engineering Nanomedicines using Stimuli-Responsive Biomaterials. Advanced Drug Delivery Reviews. 2012, 64 (11): 1021-30. PMID: 22266128
  • Wang J, Byrne JD, Napier ME, DeSimone JM. More Effective Nanomedicines through Particle Design. Small. 2011, 7 (14): 1919-31. PMID: 21695781
  • Parrott M, Luft JC, Byrne JD, Fain JH, Napier ME, DeSimone JM. Tunable Bifunctional Silyl Ether Cross-linkers for the Design of Acid-Sensitive Biomaterials. Journal of the American Chemical Society. 2010, 132 (50): 17928-17932. PMID: 21105720
  • Betancourt T, Byrne JD, Sunaryo N, Crowder SW, Kadapakkam M, Patel S, Casciato S, Brannon-Peppas L. PEGylation Strategies for Active Targeting of PLA/PLGA Nanoparticles. Journal of Biomedical Materials Research, Part A. 2009, 91 (1): 263-276. PMID: 18980197 
  • Byrne JD, Betancourt T, Brannon-Peppas L. Active Targeting Schemes for Nanoparticle Systems in Cancer Therapeutics. Advanced Drug Delivery Reviews. 2008, 60 (15): 1615-1626. PMID: 18840489
  • Fonner J, Forciniti L, Nguyen HT, Byrne JD, Syeda-Nawaz J, Kou YF, Schmidt C. Biocompatibility Implications of Polypyrrole Techniques. Biomedical Materials. 2008, 3 (3): 34124. PMID: 18765899